Congenital Thrombocytopenic Purpura Treated by Exchange Transfusion

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Congenital Thrombocytopenic Purpura Treated by Exchange Transfusion.

The occurrence of thrombocytopenic purpura in babies born to mothers with idiopathic thrombocytopenia is a well recognized though uncommon clinical entity. Robson and Walker (1951) were able to collect from the literature only 19 definite and nine probable examples of this association. The suggestion of Epstein, Lozner, Cobbey and Davidson (1950) that this type of congenital thrombocytopenic pu...

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Congenital thrombocytopenic purpura.

The purpose of this paper is to present four cases of neonatal thrombocytopenic purpura which have been investigated fully. Although an uncommon condition, it has aroused a good deal of interest and nearly 100 instances have been recorded to date. The literature has been reviewed by Robson and Walker (1951), who collected 52 cases and added three of their own, and also by Morris (1954), who giv...

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Congenital thrombotic thrombocytopenic purpura.

BACKGROUND Congenital thrombotic thrombocytopenic purpura (TTP) is a rare, hereditary disorder. Clinically it presents as episodic microangiopathic haemolytic anaemia and thrombocytopenia with varying degrees of damage to internal organs. The condition may present in neonates, but can also present for the first time in adulthood. The prevalence of congenital TTP is particularly high in Norway, ...

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Severe immune thrombocytopenic purpura treated with plasma exchange.

Immune thrombocytopenic purpura (ITP) is a hematological disorder characterized by immunologically mediated destruction of platelets and absence of other causes of thrombocytopenia. Treatment is required when the low platelet count entails risk of serious bleeding. Steroid is the first line of management. Acute refractory ITP with very low platelet count is variably treated with high dose stero...

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Congenital and neonatal thrombocytopenic purpura.

Haemorrhagic disease due to a deficiency of blood platelets is stated to be a very rare condition in the newborn. Considerable interest has been shown in the condition recently, however, and examples are being reported with increasing frequency. Barclay (1945), Schefrin and Shechtman (1945), Waters (1946), and Landolt (1948) all review small series of cases; McAlenney and Kristan (1949) collect...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1961

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.36.186.210